Glioma Cell Invasion is Significantly Enhanced in Composite Hydrogel Matrices Composed of Chondroitin 4- and 4,6-Sulfated Glycosaminoglycans

Glioblastoma multiforme (GBM) is the most aggressive form of astrocytoma accounting for a majority of primary malignant brain tumors in the United States. Chondroitin sulfate proteoglycans (CSPGs) and their glycosaminoglycan (GAG) side chains are key constituents of the brain extracellular matrix (E...

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Udgivet i:J Mater Chem B Mater Biol Med
Main Authors: Logun, Meghan T., Bisel, Nicole S., Tanasse, Emily A., Zhao, Wujun, Gunasekera, Bhagya, Mao, Leidong, Karumbaiah, Lohitash
Format: Artigo
Sprog:Inglês
Udgivet: 2016
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5312825/
https://ncbi.nlm.nih.gov/pubmed/28217304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/C6TB01083K
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