Meprin β induces activities of A disintegrin and metalloproteinases 9, 10, and 17 by specific prodomain cleavage

Meprin β is a membrane-bound metalloprotease involved in extracellular matrix assembly and inflammatory processes in health and disease. A disintegrin and metalloproteinase (ADAM)10 and ADAM17 are physiologic relevant sheddases of inactive promeprin β, which influences its substrate repertoire and s...

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Bibliographic Details
Published in:FASEB J
Main Authors: Wichert, Rielana, Scharfenberg, Franka, Colmorgen, Cynthia, Koudelka, Tomas, Schwarz, Jeanette, Wetzel, Sebastian, Potempa, Barbara, Potempa, Jan, Bartsch, Jörg W., Sagi, Irit, Tholey, Andreas, Saftig, Paul, Rose-John, Stefan, Becker-Pauly, Christoph
Format: Artigo
Language:Inglês
Published: Federation of American Societies for Experimental Biology 2019
Subjects:
Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6902663/
https://ncbi.nlm.nih.gov/pubmed/31381863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201801371R
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