Tethering soluble meprin α in an enzyme complex to the cell surface affects IBD-associated genes

Biologic activity of proteases is mainly characterized by the substrate specificity, tissue distribution, and cellular localization. The human metalloproteases meprin α and meprin β share 41% sequence identity and exhibit a similar cleavage specificity with a preference for negatively charged amino...

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Enregistré dans:
Détails bibliographiques
Publié dans:FASEB J
Auteurs principaux: Peters, Florian, Scharfenberg, Franka, Colmorgen, Cynthia, Armbrust, Fred, Wichert, Rielana, Arnold, Philipp, Potempa, Barbara, Potempa, Jan, Pietrzik, Claus U., Häsler, Robert, Rosenstiel, Philip, Becker-Pauly, Christoph
Format: Artigo
Langue:Inglês
Publié: Federation of American Societies for Experimental Biology 2019
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6529335/
https://ncbi.nlm.nih.gov/pubmed/30916990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201802391R
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