Differences in Shedding of the Interleukin-11 Receptor by the Proteases ADAM9, ADAM10, ADAM17, Meprin α, Meprin β and MT1-MMP

Interleukin-11 (IL-11) has been associated with inflammatory conditions, bone homeostasis, hematopoiesis, and fertility. So far, these functions have been linked to classical IL-11 signaling via the membrane bound receptor (IL-11R). However, a signaling cascade via the soluble IL-11R (sIL-11R), gene...

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Bibliographic Details
Published in:Int J Mol Sci
Main Authors: Sammel, Martin, Peters, Florian, Lokau, Juliane, Scharfenberg, Franka, Werny, Ludwig, Linder, Stefan, Garbers, Christoph, Rose-John, Stefan, Becker-Pauly, Christoph
Format: Artigo
Language:Inglês
Published: MDPI 2019
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6696353/
https://ncbi.nlm.nih.gov/pubmed/31357561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20153677
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