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MT1-MMP mediates MUC1 shedding independent of TACE/ADAM17

MUC1, a transmembrane mucin, plays a critical role in embryo implantation, protection of mucosal epithelia from microbial and enzymic attack and various aspects of tumour progression. In some species, a decrease in uterine epithelial MUC1 protein and mRNA expression accompanies embryo implantation....

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Detalhes bibliográficos
Main Authors: Thathiah, Amantha, Carson, Daniel D.
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1133949/
https://ncbi.nlm.nih.gov/pubmed/15130087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20040513
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