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Arsenic sulfide induces RAG1-dependent DNA damage for cell killing by inhibiting NFATc3 in gastric cancer cells

BACKGROUND: Arsenic sulfide was found to have potential anti-cancer activities, especially in gastric cancer. However, the underlying mechanism need to be further explored. This study was aimed to investigate the mechanism of arsenic compounds on gastric cancer. METHODS: Gastric cancer cell lines we...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:J Exp Clin Cancer Res
Main Authors: Kang, Ting, Ge, Maolin, Wang, Ruiheng, Tan, Zhen, Zhang, Xiuli, Zhu, Chuanying, Liu, Han, Chen, Siyu
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6902349/
https://ncbi.nlm.nih.gov/pubmed/31822296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-019-1471-x
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