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Arsenic sulfide amplifies JQ1 toxicity via mitochondrial pathway in gastric and colon cancer cells
PURPOSE: Gastric and colon cancers have been the leading causes of cancer mortality in the world with limited therapy. Small molecules binding to bromodomains of bromodomain-containing protein 4 (BRD4) exert strong antitumor activities against hematological malignancies, while generally have limited...
Shranjeno v:
| izdano v: | Drug Des Devel Ther |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Dove Medical Press
2018
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6241694/ https://ncbi.nlm.nih.gov/pubmed/30532520 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S180976 |
| Oznake: |
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