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Arsenic sulfide combined with JQ1, chemotherapy agents, or celecoxib inhibit gastric and colon cancer cell growth

BACKGROUND: Arsenic compounds have modest cytotoxic activity in solid tumors. We investigated if arsenic sulfide (As(4)S(4)) in combination with other distinct agents could enhance its cytotoxic activity. METHODS: We used gastric and colon cancer cell lines to study the synergistic effect of As(4)S(...

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Detalhes bibliográficos
Publicado no:Drug Des Devel Ther
Main Authors: Zhang, Lian, Tong, Yingying, Zhang, Xiuli, Pan, Minggui, Chen, Siyu
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4634829/
https://ncbi.nlm.nih.gov/pubmed/26586936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S92943
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