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C16 Peptide Promotes Vascular Growth and Reduces Inflammation in a Neuromyelitis Optica Model

The goal of this study was to elucidate the mechanism of action of C16, a laminin-1 peptide that competes with αvβ3 for integrin binding, in treating neuromyelitis optica (NMO). A NMO rat model was established and specific inhibitors were used to investigate the effect of Tie2 kinase, integrin, and...

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Publicat a:Front Pharmacol
Autors principals: Chen, Haohao, Fu, Xiaoxiao, Jiang, Jinzhan, Han, Shu
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2019
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6902286/
https://ncbi.nlm.nih.gov/pubmed/31849648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.01373
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