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C16 Peptide Promotes Vascular Growth and Reduces Inflammation in a Neuromyelitis Optica Model
The goal of this study was to elucidate the mechanism of action of C16, a laminin-1 peptide that competes with αvβ3 for integrin binding, in treating neuromyelitis optica (NMO). A NMO rat model was established and specific inhibitors were used to investigate the effect of Tie2 kinase, integrin, and...
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| Publicado no: | Front Pharmacol |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6902286/ https://ncbi.nlm.nih.gov/pubmed/31849648 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.01373 |
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