Astrocytic Interleukin-15 Reduces Pathology of Neuromyelitis Optica in Mice

Astrocyte loss induced by neuromyelitis optica (NMO)-IgG and complement-dependent cytotoxicity (CDC) is the hallmark of NMO pathology. The survival of astrocytes is thought to reflect astrocyte exposure to environmental factors in the CNS and the response of astrocytes to these factors. However, sti...

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Udgivet i:Front Immunol
Main Authors: Li, Zhiguo, Han, Jinrui, Ren, Honglei, Ma, Cun-Gen, Shi, Fu-Dong, Liu, Qiang, Li, Minshu
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2018
Fag:
Immunology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5867910/
https://ncbi.nlm.nih.gov/pubmed/29616032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.00523
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