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Astrocyte-derived interleukin-15 exacerbates ischemic brain injury via propagation of cellular immunity
Astrocytes are believed to bridge interactions between infiltrating lymphocytes and neurons during brain ischemia, but the mechanisms for this action are poorly understood. Here we found that interleukin-15 (IL-15) is dramatically up-regulated in astrocytes of postmortem brain tissues from patients...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5255606/ https://ncbi.nlm.nih.gov/pubmed/27994144 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1612930114 |
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