Diagnostic Profiling of the Human Public IgM Repertoire With Scalable Mimotope Libraries

Specific antibody reactivities are routinely used as biomarkers, but the antibody repertoire reactivity (igome) profiles are still neglected. Here, we propose rationally designed peptide arrays as efficient probes for these system level biomarkers. Most IgM antibodies are characterized by few somati...

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Udgivet i:Front Immunol
Main Authors: Pashov, Anastas, Shivarov, Velizar, Hadzhieva, Maya, Kostov, Victor, Ferdinandov, Dilyan, Heintz, Karen-Marie, Pashova, Shina, Todorova, Milena, Vassilev, Tchavdar, Kieber-Emmons, Thomas, Meza-Zepeda, Leonardo A., Hovig, Eivind
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2019
Fag:
Immunology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6901697/
https://ncbi.nlm.nih.gov/pubmed/31849974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.02796
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