Diagnostic Profiling of the Human Public IgM Repertoire With Scalable Mimotope Libraries

Specific antibody reactivities are routinely used as biomarkers, but the antibody repertoire reactivity (igome) profiles are still neglected. Here, we propose rationally designed peptide arrays as efficient probes for these system level biomarkers. Most IgM antibodies are characterized by few somati...

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Vydáno v:Front Immunol
Hlavní autoři: Pashov, Anastas, Shivarov, Velizar, Hadzhieva, Maya, Kostov, Victor, Ferdinandov, Dilyan, Heintz, Karen-Marie, Pashova, Shina, Todorova, Milena, Vassilev, Tchavdar, Kieber-Emmons, Thomas, Meza-Zepeda, Leonardo A., Hovig, Eivind
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2019
Témata:
Immunology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6901697/
https://ncbi.nlm.nih.gov/pubmed/31849974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.02796
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