Diagnostic Profiling of the Human Public IgM Repertoire With Scalable Mimotope Libraries

Specific antibody reactivities are routinely used as biomarkers, but the antibody repertoire reactivity (igome) profiles are still neglected. Here, we propose rationally designed peptide arrays as efficient probes for these system level biomarkers. Most IgM antibodies are characterized by few somati...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Pashov, Anastas, Shivarov, Velizar, Hadzhieva, Maya, Kostov, Victor, Ferdinandov, Dilyan, Heintz, Karen-Marie, Pashova, Shina, Todorova, Milena, Vassilev, Tchavdar, Kieber-Emmons, Thomas, Meza-Zepeda, Leonardo A., Hovig, Eivind
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6901697/
https://ncbi.nlm.nih.gov/pubmed/31849974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.02796
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