Clinically Approved Drugs Inhibit the Staphylococcus aureus Multidrug NorA Efflux Pump and Reduce Biofilm Formation

Staphylococcus aureus has acquired resistance to antibiotics since their first use. The S. aureus protein NorA, an efflux pump belonging to the major facilitator superfamily (MFS), contributes to resistance to fluoroquinolones (e.g., ciprofloxacin), biocides, dyes, quaternary ammonium compounds, and...

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Bibliografske podrobnosti
izdano v:Front Microbiol
Main Authors: Zimmermann, Saskia, Klinger-Strobel, Mareike, Bohnert, Jürgen A., Wendler, Sindy, Rödel, Jürgen, Pletz, Mathias W., Löffler, Bettina, Tuchscherr, Lorena
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2019
Teme:
Microbiology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6901667/
https://ncbi.nlm.nih.gov/pubmed/31849901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2019.02762
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