Clinically Approved Drugs Inhibit the Staphylococcus aureus Multidrug NorA Efflux Pump and Reduce Biofilm Formation

Staphylococcus aureus has acquired resistance to antibiotics since their first use. The S. aureus protein NorA, an efflux pump belonging to the major facilitator superfamily (MFS), contributes to resistance to fluoroquinolones (e.g., ciprofloxacin), biocides, dyes, quaternary ammonium compounds, and...

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Detalles Bibliográficos
Publicado en:Front Microbiol
Main Authors: Zimmermann, Saskia, Klinger-Strobel, Mareike, Bohnert, Jürgen A., Wendler, Sindy, Rödel, Jürgen, Pletz, Mathias W., Löffler, Bettina, Tuchscherr, Lorena
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2019
Assuntos:
Microbiology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6901667/
https://ncbi.nlm.nih.gov/pubmed/31849901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2019.02762
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