Clinically Approved Drugs Inhibit the Staphylococcus aureus Multidrug NorA Efflux Pump and Reduce Biofilm Formation

Staphylococcus aureus has acquired resistance to antibiotics since their first use. The S. aureus protein NorA, an efflux pump belonging to the major facilitator superfamily (MFS), contributes to resistance to fluoroquinolones (e.g., ciprofloxacin), biocides, dyes, quaternary ammonium compounds, and...

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Detalhes bibliográficos
Publicado no:Front Microbiol
Main Authors: Zimmermann, Saskia, Klinger-Strobel, Mareike, Bohnert, Jürgen A., Wendler, Sindy, Rödel, Jürgen, Pletz, Mathias W., Löffler, Bettina, Tuchscherr, Lorena
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Microbiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6901667/
https://ncbi.nlm.nih.gov/pubmed/31849901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2019.02762
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