ASCL1 is a MYCN- and LMO1-dependent member of the adrenergic neuroblastoma core regulatory circuitry

A heritable polymorphism within regulatory sequences of the LMO1 gene is associated with its elevated expression and increased susceptibility to develop neuroblastoma, but the oncogenic pathways downstream of the LMO1 transcriptional co-regulatory protein are unknown. Our ChIP-seq and RNA-seq analys...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Nat Commun
Hlavní autoři: Wang, Lu, Tan, Tze King, Durbin, Adam D., Zimmerman, Mark W., Abraham, Brian J., Tan, Shi Hao, Ngoc, Phuong Cao Thi, Weichert-Leahey, Nina, Akahane, Koshi, Lawton, Lee N., Rokita, Jo Lynne, Maris, John M., Young, Richard A., Look, A. Thomas, Sanda, Takaomi
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2019
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6901540/
https://ncbi.nlm.nih.gov/pubmed/31819055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-13515-5
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky