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Oxidation and alkylation stresses activate ribosome-quality control
Oxidation and alkylation of nucleobases are known to disrupt their base-pairing properties within RNA. It is, however, unclear whether organisms have evolved general mechanism(s) to deal with this damage. Here we show that the mRNA-surveillance pathway of no-go decay and the associated ribosome-qual...
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| Publicado no: | Nat Commun |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6901537/ https://ncbi.nlm.nih.gov/pubmed/31819057 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-13579-3 |
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