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Mitochondria ubiquitin ligase, MARCH5 resolves hepatitis B virus X protein aggregates in the liver pathogenesis

Infection of hepatitis B virus (HBV) increase the incidence of chronic liver disease and hepatocellular carcinoma (HCC). The hepatitis B viral x (HBx) protein encoded by the HBV genome contributes to the pathogenesis of HCC and thus, negative regulation of HBx is beneficial for the alleviation of th...

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Bibliografiske detaljer
Udgivet i:Cell Death Dis
Main Authors: Yoo, Young-Suk, Park, Yeon-Ji, Lee, Ho-Soo, Oanh, Nguyen Thi Kim, Cho, Mi-Young, Heo, June, Lee, Eun-Seo, Cho, Hyeseon, Park, Yong-Yea, Cho, Hyeseong
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6901512/
https://ncbi.nlm.nih.gov/pubmed/31819032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-2175-z
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