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The Auto-ubiquitylation of E3 Ubiquitin-protein Ligase Chfr at G(2) Phase Is Required for Accumulation of Polo-like Kinase 1 and Mitotic Entry in Mammalian Cells
The E3 ubiquitin-protein ligase Chfr is a mitotic stress checkpoint protein that delays mitotic entry in response to microtubule damage; however, the molecular mechanism by which Chfr accomplishes this remains elusive. Here, we show that Chfr levels are elevated in response to microtubule-damaging s...
সংরক্ষণ করুন:
| প্রধান লেখক: | , , , , , |
|---|---|
| বিন্যাস: | Artigo |
| ভাষা: | Inglês |
| প্রকাশিত: |
American Society for Biochemistry and Molecular Biology
2011
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| বিষয়গুলি: | |
| অনলাইন ব্যবহার করুন: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3162422/ https://ncbi.nlm.nih.gov/pubmed/21768102 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.231803 |
| ট্যাগগুলো: |
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