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Overexpression of corticotropin-releasing factor in the nucleus accumbens enhances the reinforcing effects of nicotine in intact female versus male and ovariectomized female rats

This study assessed the role of stress systems in the nucleus accumbens (NAc) in promoting sex differences in the reinforcing effects of nicotine. Intravenous self-administration (IVSA) of various doses of nicotine was compared following overexpression of corticotropin-releasing factor (CRF) in the...

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Detalhes bibliográficos
Publicado no:Neuropsychopharmacology
Main Authors: Uribe, Kevin P., Correa, Victor L., Pinales, Briana E., Flores, Rodolfo J., Cruz, Bryan, Shan, Zhiying, Bruijnzeel, Adriaan W., Khan, Arshad M., O’Dell, Laura E.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6901467/
https://ncbi.nlm.nih.gov/pubmed/31614362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41386-019-0543-0
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