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Amino acid modulation of dopamine in the nucleus accumbens mediates sex differences in nicotine withdrawal

The aversive effect of nicotine withdrawal is greater in female versus male rats, and we postulate that this sex difference is mediated in the nucleus accumbens (NAc). Nicotine withdrawal induces decreases in NAc dopamine and increases in acetylcholine (ACh) levels in male rats. To our knowledge, th...

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Bibliografiske detaljer
Udgivet i:Addict Biol
Main Authors: Carcoba, Luis M., Flores, Rodolfo J., Natividad, Luis A., O’Dell, Laura E.
Format: Artigo
Sprog:Inglês
Udgivet: 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5878145/
https://ncbi.nlm.nih.gov/pubmed/28940989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/adb.12556
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