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Amino acid modulation of dopamine in the nucleus accumbens mediates sex differences in nicotine withdrawal

The aversive effect of nicotine withdrawal is greater in female versus male rats, and we postulate that this sex difference is mediated in the nucleus accumbens (NAc). Nicotine withdrawal induces decreases in NAc dopamine and increases in acetylcholine (ACh) levels in male rats. To our knowledge, th...

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Bibliographic Details
Published in:Addict Biol
Main Authors: Carcoba, Luis M., Flores, Rodolfo J., Natividad, Luis A., O’Dell, Laura E.
Format: Artigo
Language:Inglês
Published: 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5878145/
https://ncbi.nlm.nih.gov/pubmed/28940989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/adb.12556
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