Interaction between androgen receptor and coregulator SLIRP is regulated by Ack1 tyrosine kinase and androgen

Aberrant activation of the androgen receptor (AR) may play a critical role in castration resistant prostate cancer. After ligand binding, AR is recruited to the androgen responsive element (ARE) sequences on the DNA where AR interaction with coactivators and corepressors modulates transcription. We...

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Vydáno v:Sci Rep
Hlavní autoři: De Silva, Dinuka, Zhang, Zhentao, Liu, Yuanbo, Parker, Joel S., Xu, Chenxi, Cai, Ling, Wang, Gang Greg, Earp, H. Shelton, Whang, Young E.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6901447/
https://ncbi.nlm.nih.gov/pubmed/31819114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-55057-2
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