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Activated Cdc42-associated kinase Ack1 promotes prostate cancer progression via androgen receptor tyrosine phosphorylation

Activation of the androgen receptor (AR) may play a role in androgen-independent progression of prostate cancer. Multiple mechanisms of AR activation, including stimulation by tyrosine kinases, have been postulated. We and others have recently shown involvement of activated Cdc42-associated tyrosine...

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Detalhes bibliográficos
Main Authors: Mahajan, Nupam P., Liu, Yuanbo, Majumder, Samarpan, Warren, Maria R., Parker, Carol E., Mohler, James L., Earp, H. Shelton, Whang, Young E.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895968/
https://ncbi.nlm.nih.gov/pubmed/17494760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0700420104
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