Effect of Ack1 Tyrosine Kinase Inhibitor on Ligand-Independent Androgen Receptor Activity

BACKGROUND: Androgen receptor (AR) plays a critical role in the progression of both androgen-dependent and androgen-independent prostate cancer (AIPC). Ligand-independent activation of AR in AIPC or castration resistant prostate cancer (CRPC) is often associated with poor prognosis. Recently, tyrosi...

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Hlavní autoři: Mahajan, Kiran, Challa, Sridevi, Coppola, Domenico, Lawrence, Harshani, Luo, Yunting, Gevariya, Harsukh, Zhu, Weiwei, Chen, Y. Ann, Lawrence, Nicholas J., Mahajan, Nupam P.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3953126/
https://ncbi.nlm.nih.gov/pubmed/20623637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pros.21163
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