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Regulator of G-protein signaling (RGS) proteins as drug targets: Progress and future potentials

G protein–coupled receptors (GPCRs) play critical roles in regulating processes such as cellular homeostasis, responses to stimuli, and cell signaling. Accordingly, GPCRs have long served as extraordinarily successful drug targets. It is therefore not surprising that the discovery in the mid-1990s o...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Biol Chem
Hauptverfasser: O'Brien, Joseph B., Wilkinson, Joshua C., Roman, David L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6901330/
https://ncbi.nlm.nih.gov/pubmed/31636120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.REV119.007060
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