BET protein targeting suppresses the PD-1/PD-L1 pathway in triple-negative breast cancer and elicits anti-tumor immune response

Therapeutic strategies aiming to leverage anti-tumor immunity are being intensively investigated as they show promising results in cancer therapy. The PD-1/PD-L1 pathway constitutes an important target to restore functional anti-tumor immune response. Here, we report that BET protein inhibition supp...

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Gepubliceerd in:Cancer Lett
Hoofdauteurs: Andrieu, Guillaume P., Shafran, Jordan S., Smith, Charlotte L., Belkina, Anna C., Casey, Allison N., Jafari, Naser, Denis, Gerald V.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2019
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6901183/
https://ncbi.nlm.nih.gov/pubmed/31473251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2019.08.013
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