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BET Proteins Exhibit Transcriptional and Functional Opposition in the Epithelial-to-mesenchymal Transition

Transcriptional programs in embryogenesis and cancer, such as the epithelial-to-mesenchymal transition (EMT), ensure cellular plasticity, an essential feature of carcinoma progression. As effectors of signal transduction, the bromodomain and extraterminal (BET) proteins are well suited to support pl...

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Detalhes bibliográficos
Publicado no:Mol Cancer Res
Main Authors: Andrieu, Guillaume P., Denis, Gerald V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5882530/
https://ncbi.nlm.nih.gov/pubmed/29437854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-17-0568
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