Intravitreal Therapy Against the Complement Factor C5 Prevents Retinal Degeneration in an Experimental Autoimmune Glaucoma Model

In glaucoma, studies revealed an involvement of the complement system. In an experimental autoimmune glaucoma model, immunization with an optic nerve homogenate antigen (ONA) led to retinal ganglion cell (RGC) loss, while intraocular pressure (IOP) remained unchanged. Here, we investigated the thera...

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Enregistré dans:
Détails bibliographiques
Publié dans:Front Pharmacol
Auteurs principaux: Reinehr, Sabrina, Gomes, Sara C., Gassel, Caroline J., Asaad, M. Ali, Stute, Gesa, Schargus, Marc, Dick, H. Burkhard, Joachim, Stephanie C.
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2019
Sujets:
Pharmacology
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6901014/
https://ncbi.nlm.nih.gov/pubmed/31849650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.01381
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