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Intravitreal Therapy Against the Complement Factor C5 Prevents Retinal Degeneration in an Experimental Autoimmune Glaucoma Model

In glaucoma, studies revealed an involvement of the complement system. In an experimental autoimmune glaucoma model, immunization with an optic nerve homogenate antigen (ONA) led to retinal ganglion cell (RGC) loss, while intraocular pressure (IOP) remained unchanged. Here, we investigated the thera...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Reinehr, Sabrina, Gomes, Sara C., Gassel, Caroline J., Asaad, M. Ali, Stute, Gesa, Schargus, Marc, Dick, H. Burkhard, Joachim, Stephanie C.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6901014/
https://ncbi.nlm.nih.gov/pubmed/31849650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.01381
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