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S100B immunization triggers NFκB and complement activation in an autoimmune glaucoma model

In glaucoma, latest studies revealed an involvement of the complement system with and without an elevated intraocular pressure. In the experimental autoimmune glaucoma model, immunization with antigens, such as S100B, lead to retinal ganglion cell (RGC) loss and optic nerve degeneration after 28 day...

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Bibliografiska uppgifter
I publikationen:Sci Rep
Huvudupphovsmän: Reinehr, Sabrina, Reinhard, Jacqueline, Gandej, Marcel, Gottschalk, Ivo, Stute, Gesa, Faissner, Andreas, Dick, H. Burkhard, Joachim, Stephanie C.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group UK 2018
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6026137/
https://ncbi.nlm.nih.gov/pubmed/29959432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-28183-6
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