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Genetic and Pharmacological Inhibition of Retinoic Acid Receptor γ Function Promotes Endochondral Bone Formation

The nuclear retinoic acid receptors (RARs) play key roles in skeletal development and endochondral ossification. Previously we showed that RARγ regulates chondrogenesis and that pharmacological activation of RARγ blocked heterotopic ossification (HO), pathology in which endochondral bone forms in so...

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Détails bibliographiques
Publié dans:J Orthop Res
Auteurs principaux: Uchibe, Kenta, Son, Jiyeon, Larmour, Colleen, Pacifici, Maurizio, Enomoto-Iwamoto, Motomi, Iwamoto, Masahiro
Format: Artigo
Langue:Inglês
Publié: 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6900928/
https://ncbi.nlm.nih.gov/pubmed/27325507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jor.23347
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