Potent Inhibition of Heterotopic Ossification by Nuclear Retinoic Acid Receptor γ Agonists

Heterotopic ossification (HO) consists of ectopic bone formation within soft tissues following surgery or trauma and can have debilitating consequences, but no definitive cure is available. Here we show that HO was essentially prevented in mice receiving nuclear retinoic acid receptor γ (RARγ) agoni...

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Detalhes bibliográficos
Main Authors: Shimono, Kengo, Tung, Wei-en, Macolino, Christine, Chi, Amber Hsu-Tsai, Didizian, Johanna J., Mundy, Christina, Chandraratna, Roshantha A., Mishina, Yuji, Iwamoto, Motomi Enomoto, Pacifici, Maurizio, Iwamoto, Masahiro
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3073031/
https://ncbi.nlm.nih.gov/pubmed/21460849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.2334
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