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Genetic and Pharmacological Inhibition of Retinoic Acid Receptor γ Function Promotes Endochondral Bone Formation

The nuclear retinoic acid receptors (RARs) play key roles in skeletal development and endochondral ossification. Previously we showed that RARγ regulates chondrogenesis and that pharmacological activation of RARγ blocked heterotopic ossification (HO), pathology in which endochondral bone forms in so...

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Detalhes bibliográficos
Publicado no:J Orthop Res
Main Authors: Uchibe, Kenta, Son, Jiyeon, Larmour, Colleen, Pacifici, Maurizio, Enomoto-Iwamoto, Motomi, Iwamoto, Masahiro
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6900928/
https://ncbi.nlm.nih.gov/pubmed/27325507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jor.23347
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