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Genetic and Pharmacological Inhibition of Retinoic Acid Receptor γ Function Promotes Endochondral Bone Formation
The nuclear retinoic acid receptors (RARs) play key roles in skeletal development and endochondral ossification. Previously we showed that RARγ regulates chondrogenesis and that pharmacological activation of RARγ blocked heterotopic ossification (HO), pathology in which endochondral bone forms in so...
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| Veröffentlicht in: | J Orthop Res |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6900928/ https://ncbi.nlm.nih.gov/pubmed/27325507 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jor.23347 |
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