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Predictive Multivariate Linear Regression Analysis Guides Successful Catalytic Enantioselective Minisci Reactions of Diazines

[Image: see text] The Minisci reaction is one of the most direct and versatile methods for forging new carbon–carbon bonds onto basic heteroarenes: a broad subset of compounds ubiquitous in medicinal chemistry. While many Minisci-type reactions result in new stereocenters, control of the absolute st...

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Publicat a:J Am Chem Soc
Autors principals: Reid, Jolene P., Proctor, Rupert S. J., Sigman, Matthew S., Phipps, Robert J.
Format: Artigo
Idioma:Inglês
Publicat: American Chemical Society 2019
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6900758/
https://ncbi.nlm.nih.gov/pubmed/31710210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.9b11658
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