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Holistic Prediction of Enantioselectivity in Asymmetric Catalysis
When faced with unfamiliar reaction space, synthetic chemists typically apply reported conditions (reagents, catalyst, solvent, additives) from closely-related reactions to new substrate types. Unfortunately, this approach often fails due to subtle, albeit important, differences in reaction requirem...
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| Publicado no: | Nature |
|---|---|
| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6641578/ https://ncbi.nlm.nih.gov/pubmed/31316193 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-019-1384-z |
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