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Glia-derived exosomal miR-274 targets Sprouty in trachea and synaptic boutons to modulate growth and responses to hypoxia

Secreted exosomal microRNAs (miRNAs) mediate interorgan/tissue communications by modulating target gene expression, thereby regulating developmental and physiological functions. However, the source, route, and function in target cells have not been formally established for specific miRNAs. Here, we...

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Dettagli Bibliografici
Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Tsai, Yi-Wei, Sung, Hsin-Ho, Li, Jian-Chiuan, Yeh, Chun-Yen, Chen, Pei-Yi, Cheng, Ying-Ju, Chen, Chun-Hong, Tsai, Yu-Chen, Chien, Cheng-Ting
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6900535/
https://ncbi.nlm.nih.gov/pubmed/31666321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1902537116
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