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Glia and Muscle Sculpt Neuromuscular Arbors by Engulfing Destabilized Synaptic Boutons and Shed Presynaptic Debris

Synapse remodeling is an extremely dynamic process, often regulated by neural activity. Here we show during activity-dependent synaptic growth at the Drosophila NMJ many immature synaptic boutons fail to form stable postsynaptic contacts, are selectively shed from the parent arbor, and degenerate or...

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Bibliografiske detaljer
Main Authors: Fuentes-Medel, Yuly, Logan, Mary A., Ashley, James, Ataman, Bulent, Budnik, Vivian, Freeman, Marc R.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2724735/
https://ncbi.nlm.nih.gov/pubmed/19707574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1000184
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