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Glia-derived exosomal miR-274 targets Sprouty in trachea and synaptic boutons to modulate growth and responses to hypoxia

Secreted exosomal microRNAs (miRNAs) mediate interorgan/tissue communications by modulating target gene expression, thereby regulating developmental and physiological functions. However, the source, route, and function in target cells have not been formally established for specific miRNAs. Here, we...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Tsai, Yi-Wei, Sung, Hsin-Ho, Li, Jian-Chiuan, Yeh, Chun-Yen, Chen, Pei-Yi, Cheng, Ying-Ju, Chen, Chun-Hong, Tsai, Yu-Chen, Chien, Cheng-Ting
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6900535/
https://ncbi.nlm.nih.gov/pubmed/31666321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1902537116
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