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Differentiation of leukemic blasts is not completely blocked in acute myeloid leukemia

Hematopoiesis, the formation of blood cells, involves the hierarchical differentiation of immature blast cells into mature, functional cell types and lineages of the immune system. Hematopoietic stem cells precisely regulate self-renewal versus differentiation to balance the production of blood cell...

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Библиографические подробности
Опубликовано в: :Proc Natl Acad Sci U S A
Главные авторы: Agarwal, Anupriya, Bolosky, William J., Wilson, David B., Eide, Christopher A., Olson, Susan B., Fan, Guang, Druker, Brian J.
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2019
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6900505/
https://ncbi.nlm.nih.gov/pubmed/31754026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1904091116
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