CRISPR/Cas9 gene correction of HbH-CS thalassemia-induced pluripotent stem cells

Haemoglobin (Hb) H-constant spring (CS) alpha thalassaemia (- -/-α(CS)) is the most common type of nondeletional Hb H disease in southern China. The CRISPR/Cas9-based gene correction of patient-specific induced pluripotent stem cells (iPSCs) and cell transplantation now represent a therapeutic solut...

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Bibliografiske detaljer
Udgivet i:Ann Hematol
Main Authors: Yingjun, Xie, Yuhuan, Xie, Yuchang, Chen, Dongzhi, Li, Ding, Wang, Bing, Song, Yi, Yang, Dian, Lu, Yanting, Xue, Zeyu, Xiong, Nengqing, Liu, Diyu, Chen, Xiaofang, Sun
Format: Artigo
Sprog:Inglês
Udgivet: Springer Berlin Heidelberg 2019
Fag:
Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6900276/
https://ncbi.nlm.nih.gov/pubmed/31495903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00277-019-03763-2
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