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CRISPR/Cas9 gene correction of HbH-CS thalassemia-induced pluripotent stem cells
Haemoglobin (Hb) H-constant spring (CS) alpha thalassaemia (- -/-α(CS)) is the most common type of nondeletional Hb H disease in southern China. The CRISPR/Cas9-based gene correction of patient-specific induced pluripotent stem cells (iPSCs) and cell transplantation now represent a therapeutic solut...
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| Udgivet i: | Ann Hematol |
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| Main Authors: | , , , , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Springer Berlin Heidelberg
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6900276/ https://ncbi.nlm.nih.gov/pubmed/31495903 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00277-019-03763-2 |
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