Application of affinity capillary electrophoresis for charge heterogeneity profiling of biopharmaceuticals

Charge heterogeneity profiling is important for the quality control (QC) of biopharmaceuticals. Because of the increasing complexity of these therapeutic entities [1], the development of alternative analytical techniques is needed. In this work, flow‐through partial‐filling affinity capillary electr...

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Detalles Bibliográficos
Publicado en:Electrophoresis
Main Authors: Hutanu, Andrei, Kiessig, Steffen, Bathke, Andrea, Ketterer, Rolf, Riner, Sonja, Olaf Stracke, Jan, Wild, Markus, Moritz, Bernd
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2019
Assuntos:
Part V. Proteins, Proteomics and 2D
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6900010/
https://ncbi.nlm.nih.gov/pubmed/31560789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/elps.201900233
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