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Genetic background modifies CNS‐mediated sensorimotor decline in the AD‐BXD mouse model of genetic diversity in Alzheimer's disease

Many patients with Alzheimer's dementia (AD) also exhibit noncognitive symptoms such as sensorimotor deficits, which can precede the hallmark cognitive deficits and significantly impact daily activities and an individual's ability to live independently. However, the mechanisms underlying s...

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Bibliographische Detailangaben
Veröffentlicht in:Genes Brain Behav
Hauptverfasser: O'Connell, Kristen M. S., Ouellette, Andrew R., Neuner, Sarah M., Dunn, Amy R., Kaczorowski, Catherine C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Blackwell Publishing Ltd 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6899779/
https://ncbi.nlm.nih.gov/pubmed/31381246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/gbb.12603
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