Artemisinin–(Iso)quinoline Hybrids by C−H Activation and Click Chemistry: Combating Multidrug‐Resistant Malaria

A substantial challenge worldwide is emergent drug resistance in malaria parasites against approved drugs, such as chloroquine (CQ). To address these unsolved CQ resistance issues, only rare examples of artemisinin (ART)‐based hybrids have been reported. Moreover, protein targets of such hybrids hav...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Angew Chem Int Ed Engl
Päätekijät: Çapcı, Aysun, Lorion, Mélanie M., Wang, Hui, Simon, Nina, Leidenberger, Maria, Borges Silva, Mariana C., Moreira, Diogo R. M., Zhu, Yongping, Meng, Yuqing, Chen, Jia Yun, Lee, Yew Mun, Friedrich, Oliver, Kappes, Barbara, Wang, Jigang, Ackermann, Lutz, Tsogoeva, Svetlana B.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: John Wiley and Sons Inc. 2019
Aiheet:
Research Articles
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6899722/
https://ncbi.nlm.nih.gov/pubmed/31290221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201907224
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