Fsp1-Mediated Lineage Tracing Fails to Detect the Majority of Disseminating Cells Undergoing EMT

Epithelial-to-mesenchymal transition (EMT) has long been thought to be crucial for metastasis. Recently a study challenged this idea by demonstrating that metastases were seeded by tumor cells that were not marked by an EMT lineage-tracing reporter on the basis of the expression of the mesenchymal m...

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Udgivet i:Cell Rep
Main Authors: Bornes, Laura, van Scheppingen, Roan Hugo, Beerling, Evelyne, Schelfhorst, Tim, Ellenbroek, Saskia Inge Johanna, Seinstra, Danielle, van Rheenen, Jacco
Format: Artigo
Sprog:Inglês
Udgivet: Cell Press 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6899519/
https://ncbi.nlm.nih.gov/pubmed/31775027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2019.10.107
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