Plasticity between Epithelial and Mesenchymal States Unlinks EMT from Metastasis-Enhancing Stem Cell Capacity

Forced overexpression and/or downregulation of proteins regulating epithelial-to-mesenchymal transition (EMT) has been reported to alter metastasis by changing migration and stem cell capacity of tumor cells. However, these manipulations artificially keep cells in fixed states, while in vivo cells m...

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Publicat a:Cell Rep
Autors principals: Beerling, Evelyne, Seinstra, Daniëlle, de Wit, Elzo, Kester, Lennart, van der Velden, Daphne, Maynard, Carrie, Schäfer, Ronny, van Diest, Paul, Voest, Emile, van Oudenaarden, Alexander, Vrisekoop, Nienke, van Rheenen, Jacco
Format: Artigo
Idioma:Inglês
Publicat: Cell Press 2016
Matèries:
Report
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4802222/
https://ncbi.nlm.nih.gov/pubmed/26947068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.02.034
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