Plasticity between Epithelial and Mesenchymal States Unlinks EMT from Metastasis-Enhancing Stem Cell Capacity

Forced overexpression and/or downregulation of proteins regulating epithelial-to-mesenchymal transition (EMT) has been reported to alter metastasis by changing migration and stem cell capacity of tumor cells. However, these manipulations artificially keep cells in fixed states, while in vivo cells m...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Beerling, Evelyne, Seinstra, Daniëlle, de Wit, Elzo, Kester, Lennart, van der Velden, Daphne, Maynard, Carrie, Schäfer, Ronny, van Diest, Paul, Voest, Emile, van Oudenaarden, Alexander, Vrisekoop, Nienke, van Rheenen, Jacco
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2016
Assuntos:
Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4802222/
https://ncbi.nlm.nih.gov/pubmed/26947068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.02.034
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