Disruption of the Key Ca(2+) Binding Site in the Selectivity Filter of Neuronal Voltage-Gated Calcium Channels Inhibits Channel Trafficking

Voltage-gated calcium channels are exquisitely Ca(2+) selective, conferred primarily by four conserved pore-loop glutamate residues contributing to the selectivity filter. There has been little previous work directly measuring whether the trafficking of calcium channels requires their ability to bin...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Cell Rep
Egile Nagusiak: Meyer, James O., Dahimene, Shehrazade, Page, Karen M., Ferron, Laurent, Kadurin, Ivan, Ellaway, Joseph I.J., Zhao, Pengxiang, Patel, Tarun, Rothwell, Simon W., Lin, Peipeng, Pratt, Wendy S., Dolphin, Annette C.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Cell Press 2019
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6899504/
https://ncbi.nlm.nih.gov/pubmed/31577951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2019.08.079
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