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Checkpoint inhibitor failure in hypermutated and mismatch repair-mutated recurrent high-grade gliomas

BACKGROUND: Recurrent high-grade gliomas in adults remain a deadly cancer with median survival of less than 1 year. In the absence of effective agents, immunotherapy with checkpoint inhibitors has been adopted as a potentially beneficial next step for recurrences with hypermutated or mismatch repair...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Neurooncol Pract
Päätekijät: Ahmad, Haroon, Fadul, Camilo E, Schiff, David, Purow, Benjamin
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Oxford University Press 2019
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6899050/
https://ncbi.nlm.nih.gov/pubmed/31832212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nop/npz016
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