Quantitative whole-brain 3D imaging of tyrosine hydroxylase-labeled neuron architecture in the mouse MPTP model of Parkinson's disease

Parkinson's disease (PD) is a basal ganglia movement disorder characterized by progressive degeneration of the nigrostriatal dopaminergic system. Immunohistochemical methods have been widely used for characterization of dopaminergic neuronal injury in animal models of PD, including the MPTP (1-...

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Detalhes bibliográficos
Publicado no:Dis Model Mech
Main Authors: Roostalu, Urmas, Salinas, Casper B. G., Thorbek, Ditte D., Skytte, Jacob L., Fabricius, Katrine, Barkholt, Pernille, John, Linu M., Jurtz, Vanessa Isabell, Knudsen, Lotte Bjerre, Jelsing, Jacob, Vrang, Niels, Hansen, Henrik H., Hecksher-Sørensen, Jacob
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6899010/
https://ncbi.nlm.nih.gov/pubmed/31704726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.042200
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